The overview SearchIntroductionBasic structure of cartilage and also boneCartilageTypes of cartilageBoneBone cellsTypes of boneOssificationKeywordsSelf check optionsQuizMoviesShotgun Spongy BoneShotgun dense BoneShotgun Bone Marrow SmearShotgun Hyaline Cartilage Bone

What is bone for?

Support - bones consist of a structural frame for the body, and administer attachment sites for muscles. Protection - security of interior organs - i.e. Brain, heart and lungs, Assisting movement.

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Mineral homeostasis - the bone is a save for calcium and phosphorus Blood cabinet production - takes location in the bone marrow.

What is bone consisted of of?

Bone is a strong, flexible and semi-rigid supporting tissue. It have the right to withstand compression forces, and also yet it have the right to bend. Choose cartilage, and also other varieties of connective tissue, bone is comprised of Cells and also Extracellular matrix:

Cells - i m sorry in bone are called osteoblasts and osteocytes, (osteo - bone). Over there are additionally two various other cell types: osteoprogenitor cell and osteoclasts.

Find out an ext about the species of cells uncovered in bone

Extracellular matrix, i m sorry is consisted of of an organic matrix (30%) containing proteoglycans (but much less than cartilage), glycosaminoglycans, glycoproteins, osteonectin (anchors bone mineral come collagen) and also osteocalcin (calcium binding protein). There space collagen fibres (mostly form I (90%), through some type V). Only 25% of bone is water. Practically 70% that bone is consisted of of bone mineral called hydroxyapatite.

Before the extracellular matrix is calcified, the organization is referred to as osteoid (bone-like) tissue. When the concentrations of calcium and phosphate ions rise high enough, they room deposited into the extracellular matrix, and also the bone calcifies. Impaired calcification (i.e. In diseases such together rickets) leader to higher levels that osteoid tissue than normal. Calcification occurs only in existence of collagen fibres - salt crystallize in the spaces in between the fibres, climate accumulate about them.

Bone is resistant come bending, twisting, compression and also stretch. It is hard, because it is calcified, and the collagen fibres help the bone to resist tensile stresses. If girlfriend dissolve away the calcium salt of bone, climate the bone becomes rubbery since of the collagen fibres which space left behind.

Types that bone:


The first bone created at any kind of site is woven (or primary) bone, but this is soon changed by lamellar bone. In woven bone the collagen fibres are random. In lamellar bone, the collagen fibres have become re-modelled come become more parallel - in layers.

There are two species of mature bone:

1. Compact - which is discovered in the shafts of lengthy bones (in the diaphyses). This makes up 80% of all bone.

2. Spongy (cancellous) bone - which is discovered at the ends of long bones (in the epiphysis). This makes up 20% of all bone. This kind of bone has red bone marrow and a network that bony trabeculae.

A "periosteum" is discovered on the outside of bone. This is a thick fibrous layer, whereby muscles insert. It consists of bone forming cells. It is not discovered in the regions of bone spanned by articular cartilage.

The endosteum is the name provided to the organization that present the inner surfaces of bones.

Click below to find out about the framework of this two varieties of bone in more detail.

(Note : osteo - bone native the greek osteon which method bone)

Growth and also nourishment of bone.

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Unlike cartilage, bone has a very an excellent blood supply. Bone is riddled v blood capillaries. The main cavity contains blood vessels and is a storage for bone marrow. All of the osteocytes in bone are within 0.2mm the a capillary. The tissue liquid from the capillary will the osteocytes despite canaliculi.

There space two ways in which bone deserve to grow:

Endochondral - development of bone onto a momentary cartilage version or scaffold. Intramembranous - development of bone straight onto fibrous connective tissue. Over there is no intermediary cartilage stage. This type of ossification occurs in a couple of specialised areas such together the level bones of skull (i.e. Parietal bone), mandible, maxilla and also clavicles. Mesenchyme cells distinguish into osteoprogenitor cells, then right into osteoblasts, which secrete the bone matrix. Once the osteoblasts are embedded in the bone matrix, they are recognized as osteocytes.

Find out much more about Ossification

What following ..

When you"ve finished analysis through the part on bone and cartilage, shot drawing up a table compare the properties of bone, and cartilage:

Think about:

why bone is may be to stand up to tension and compression. Exactly how the differences in between bone and cartilage can be accounted because that in terms of the nature that the extracellular materials present in cartilage and also bone. Just how bone and also cartilage achieve their nourishment. The various names because that the cell in bone and cartilage. The various names for the outer layer of dense connective tissue.