Antacids are a class of drugs provided to treat problems caused by the acid that is created by the stomach. The stomach naturally secretes an acid referred to as hydrochloric acid that helps to failure proteins. This acid reasons the contents of the stomach to be acidic in nature, through a pH level that 2 or 3 as soon as acid secretion is active.(pH levels space a measure up of mountain in the stomach: the reduced the number, the better the acidity.)The stomach, duodenum, and esophagus are safeguarded from mountain by several protective mechanisms. When there is too lot acid or security mechanisms space inadequate, the lining the the stomach, duodenum or stomach may come to be damaged by the acid, providing rise come inflammation and ulcerations and also their miscellaneous gastrointestinal symptoms such as
Antacids mitigate acidity by neutralizing (counteracting) acid, reduce the mountain in the stomach, and also reducing the lot of acid that is refluxed into the esophagus or cleared into the duodenum. Antacids additionally work by inhibiting the task of pepsin, a cradle enzyme developed in the stomach that is energetic only in an acid atmosphere and, choose acid, is thought to it is in injurious come the lining the the stomach, duodenum, and also esophagus.
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It is vital to note that as soon as antacids space taken ~ above an empty stomach they provide acid reduction because that 20 to 40 minutes only since the antacid is rapidly cleared into the duodenum.
Antacids are used commonly for symptoms together asheartburn,nausea result from a variety of conditions together asinflammation orWhat space the species of antacids?
Some antacid products may neutralize an ext acid in the stomach than others. The means to express the capability of one antacid to neutralize acid is by identify the antacid's neutralizing capacity (ANC). The ANC is expressed as milliequivalents (mEq) of acid that is neutralized, and it measures the capacity of the antacid to neutralize acids (to a ph the 3.5 come 4). Per FDA requirements, an antacid must have actually a neutralizing volume of ≥5 mEq per dose. The most reliable antacids should have actually a high mountain neutralization capacity and also rapid gastric mountain neutralization qualities.
An antacid's start of neutralizing activity (how fast the medicine dissolves in gastric acid) varies among different antacids.
Another difference amongst the antacids is the expression of action (how lengthy it continues to neutralize mountain in the stomach).
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