Methimazole is used to act overactive thyroid (hyperthyroidism). It works by avoiding the thyroid gland from making too much thyroid hormone.

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Dosages of Methimazole:

Adult and also Pediatric Dosage Forms and Strengths

Tablet

10 mg

Dosing Considerations – should be given as Follows:

Hyperthyroidism

Adult:

Mild: 15 mg/day orally separated every 8 hrs initiallyModerate: 30-40 mg/day orally divided every 8 hours initiallySevere: 60 mg/day orally separated every 8 hrs initiallyMaintenance: 5-15 mg/day orally split every 8 hours

Pediatric:

Initial: 0.4-0.7 mg/kg/day orally split every 8 hoursMaintenance: 1/3-2/3 of initial orally dosage split every 8 hrs orallyNot come exceed 30 mg/day

Graves Disease

Adult: 10-20 mg/day orally; ~ euthyroidism is achieved, minimize dosage through 50% and carry out for 12-18 monthsPediatric: 0.2-0.5 mg/kg/day orally; ~ euthyroidism is achieved, reduce dosage by 50% and administered for 1-2 years

Thyrotoxic Crisis

20-30 mg every 6-12 hrs for the brief term, then alleviate dosage to maintain (5-15 mg/day) or minimize the frequency to every 12 hrs or every 24 hours
*
SLIDESHOW Hyperthyroidism Symptoms and Treatment view Slideshow

Common side impacts of methimazole include:

DrowsinessHepatotoxicityPolyarthritisSwellingVomiting

Rare but serious side results of methimazole include:

Persistent nausea or vomiting

This paper does not contain all possible side effects and also others may occur. Inspect with your medical professional for added information around side effects.


If your doctor has actually directed you to use this medication, your doctor or pharmacist may currently be conscious of any feasible drug interactions and also may be monitoring you because that them. Carry out not start, stop, or readjust the dosage of any medicine prior to checking v your doctor, health care provider, or pharmacist first.

Severe interactions of methimazole include:eliglustatSerious interactions of methimazole include:Methimazole has actually moderate interactions through at least 23 different drugs.Mild interactions of methimazole include:iodinated glycerolruxolitinib

This info does no contain all possible interactions or disadvantage effects. Therefore, prior to using this product, phone call your medical professional or pharmacist of every the assets you use. Keep a list of all your drugs with you, and also share this information with your doctor and pharmacist. Inspect with her health care professional or physician for extr medical advice, or if you have actually health questions, concerns, or for an ext information about this medicine.

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Warnings

This medication contains methimazole. Do not take it Northyx or Tapazole if you space allergic come methimazole or any kind of ingredients contained in this drug.

Keep the end of with of children. In case of overdose, acquire medical help or call a poison Control center immediately

ContraindicationsHypersensitivity

Short-Term Effects

See "What space Side Effects associated with utilizing Methimazole?"

Long-Term Effects

See "What are Side Effects associated with utilizing Methimazole?"

Cautions

Dosage better than 40 mg/dayConcurrent administration of other agranulocytosis-causing drugs10 times an ext potent 보다 PTU, but activity may be much less consistent

Pregnancy and also Lactation

Use methimazole throughout pregnancy only in LIFE-THREATENING emergencies when no more secure drug is availableThere is positive evidence of human fetal riskIts usage is contraindicated through the manufacturer